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View Full Version : Unrelated hla matched donor transplant vs atg+cyclosporine .


Asingh
Sun Jun 24, 2018, 06:07 AM
Diagnosed aplastic anemia 1 month back at 39 yrs age , my brother and sister are not hla matching with me . Sent for high resolution hla matching to find unrelated hla match in DATRI and other bone marrow registry .
If. I get a match which one is better unrelated matched transplant or atg + ciclisporin.
What is current treatment for 39yrs old newly diagnosed aplastic anemia otherwise healthy ?

Hopeful
Sun Jun 24, 2018, 01:07 PM
Hi Asignh,

It is my understanding that ATG+Cyclosporine is still the first-line treatment for someone your age with no matched sibling donor.

Here is a recent article on this:
http://www.bloodjournal.org/content/bloodjournal/129/11/1428.full.pdf?sso-checked=true

evansmom
Mon Jun 25, 2018, 05:25 PM
I believe Hopeful is correct.

Dishavirk
Sun Dec 30, 2018, 12:01 AM
Diagnosed aplastic anemia 1 month back at 39 yrs age , my brother and sister are not hla matching with me . Sent for high resolution hla matching to find unrelated hla match in DATRI and other bone marrow registry .
If. I get a match which one is better unrelated matched transplant or atg + ciclisporin.
What is current treatment for 39yrs old newly diagnosed aplastic anemia otherwise healthy ?

Hi

I m in same situation as u
35 years old with aplastic anemia
Diagnosed on 30 sep 2017
Went under atg+ist+Eltrombopag(150)
Wondering how r u doing??