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View Full Version : sotatercept, ace 536


vikasgoyal
Sun Oct 6, 2013, 01:56 PM
Is anyone on the forum aware of the trials going on for ace 536 or sotatercept? My initial thought reading the article is that it specifically targets Anemia in mDS patients.

http://www.clinicaltrials.gov/ct2/show/NCT01736683?term=sotatercept&rank=7

Birgitta-A
Sun Oct 6, 2013, 03:38 PM
Hi vikasgoyal,
Very interesting study with patients from many centers in the US and France.
Kind regards
Birgitta-A

riccd2001
Sun Oct 6, 2013, 05:05 PM
...There's still more to do but these are very encouraging words in the PR...:cool:

"In a phase 1 clinical study of healthy volunteers, ACE-536 produced a dose-dependent increase in red blood cells and hemoglobin levels. "

http://www.checkorphan.org/grid/news/treatment/acceleron-initiates-phase-2-study-of-ace-536-to-treat-anemia-in-patients-with-myelodysplastic-syndromes