Azacitidine for treatment of imminent relapse in MDS or AML patients
 

Was researching this, and wondering if anyone had any thoughts...

I was offered this as a 'possible' protection against relapse, even though I am in the lowest risk band for relapse...

Has anyone done this post SCT/BMT for the purpose of minimizing relapse?

Background:
http://www.ncbi.nlm.nih.gov/pubmed/21886171

http://www.ebmt.org/Contents/Resourc...0de%20Lima.pdf

I believe that Karen (handle Mausmish) was on Vidaza after transplant for either 6 months or 1 year.

Below is another trial going on at the hospital my husband had his transplant. We've met 2 patients, one in his late 30s and another in her late teens, that are doing really well 1 year post transplant, no relapse and have participated in this trial.
http://clinicaltrials.gov/show/NCT02124174

So I saw my Dr. today, and we further discussed Azacitidine as maintenance against relapse...

My prelim BMB results came back from my 6 month BMB, and I was still 100% Donor, no chimerism, 1% blasts, and no CD34+ expression... This along with my Myleoblative SCT, and total body irradiation (pre-SCT), leaves me with little to benefit from the chemo...

We decided that since things are going so well, no maintenance treatment would be used, and unless things change, I shouldn't need it...

Thanks be to God!!!! Best to all & God Bless...

Sounds like the right path. It is great to see you doing well!

That's great news Dave. Like you said if it isn't broke don't mess with it.
Glad they see it your way and you continue to sail along smoothly.
Continued success on your stellar progress.