What does extremely hypocellular mean?
I just got this report, but have not heard from my dr. yet
I've been up to 9% blasts and have always been hypocellular. Last bmb said 5-30%. So is extremely mean less than 5%? Whats all that CD stuff. I still feel fine, working and have had no treatments. Are my blasts now 1% and does low cellularity effect that %? Thanks for any answers anyone may have! FINAL PATHOLOGIC DIAGNOSIS BONE MARROW: NONLYMPHOID BLASTS, 1% OF TOTAL EVENTS, EXTREMELY HYPOCELLULAR SPECIMEN, see comment. Comment Smears prepared from material submitted for flow are extremely hypocellular. The specimen may not be representative. By flow, nonlymphoid blasts account for approximately 1% of total events. CD2 is essentially negative in the current study. The numbers of granulocytes and monocytes are extremely low. Correlation with other clinical studies is suggested for definitive diagnosis. Antibody to CD45 was used for gating. 2 smears reviewed for this study. Flow Cytometry Findings Sample viability (by dye exclusion): 99% Gating Strategy: CD45 versus side scatter. A population of CD34 positive non-lymphoid blasts accounts for approximately 1% of events. Positive for: CD33 (dim), CD13, CD34, CD117, and HLA-DR. Negative for: CD3, CD4, CD8, CD56, CD5, CD7, CD2, CD10, CD14, CD15, CD61, CD19, CD20, kappa, and lambda. Clinical History 52 M RAEB-1, repeat bone marrow to assess for progression. GENETICS CANCER CHROMOSOME ANALYSIS Indication: MDS/PRELEUKEMIA (MYELODYSPLASTIC S Status: Rule out Indication: THROMBOCYTOPENIA Status: Affected Other Reasons: RAEB-1, NEUTROPENIA RESULT Method: GTW Number of cells/colonies: 20 Band Level: 400 Karyotype: 46,XY[15] *INTERPRETATION* Normal male karyotype. The population of cells analyzed did NOT confirm that a clonal chromosome abnormality is present; however, it does not exclude the possibility that a neoplastic process exists. NOTE: Number of cells counted: 20; Number of cells analyzed: 20; number of karyograms prepared: 2 |
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