Marrowforums - ASH 2011 - L-Leucine Improves the Anemia of the 5q- Syndrome Via Activation of the mT

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ASH 2011 - L-Leucine Improves the Anemia of the 5q- Syndrome Via Activation of the mT

http://ash.confex.com/ash/2011/webpr...aper43073.html

970 L-Leucine Improves the Anemia of the 5q- Syndrome Via Activation of the mTOR (mammalian target of rapamycin) Pathway

Good News for the 5q-Syndrome (and Patients with Diamond Blackfan Anemia):

"In a case report, administration of L-Leucine to a DBA patient resulted in complete recovery of the anemia and improvement in appetite and growth parameters. We therefore hypothesized that L-Leucine could improve the anemia associated with heterozygous loss of RPS14."

"Our studies support the further evaluation of L-Leucine as a potential therapeutic agent in the treatment of the 5q- syndrome."

is a food additive. Infos on wikipedia, http://en.wikipedia.org/wiki/Leucine , procuct free available (amazon.com...) Margarete