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-   -   sotatercept, ace 536 (http://forums.marrowforums.org/showthread.php?t=3867)

vikasgoyal Sun Oct 6, 2013 12:56 PM

sotatercept, ace 536
 
Is anyone on the forum aware of the trials going on for ace 536 or sotatercept? My initial thought reading the article is that it specifically targets Anemia in mDS patients.

http://www.clinicaltrials.gov/ct2/sh...tercept&rank=7

Birgitta-A Sun Oct 6, 2013 02:38 PM

Sotatercept
 
Hi vikasgoyal,
Very interesting study with patients from many centers in the US and France.
Kind regards
Birgitta-A

riccd2001 Sun Oct 6, 2013 04:05 PM

From an earlier thread on ACE-536 (Feb.2013)
 
...There's still more to do but these are very encouraging words in the PR...:cool:

"In a phase 1 clinical study of healthy volunteers, ACE-536 produced a dose-dependent increase in red blood cells and hemoglobin levels. "

http://www.checkorphan.org/grid/news...stic-syndromes


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