We're Out of Here!
 

Hi All!

Well, it's been a good run, but I think it's time we closed down this Campath roadshow and moved on to greener pastures.

Dr. Olnes' evaluation of my latest BMB is that response is unlikely at this late date; and, given my every other week transfusion schedule, it's time to try something new.

A new therapy requires a new thread, no? So come look for me here, where I'm crowd sourcing my next therapy. I need your help researching my options.

Take Care!

Greg

Hi Greg,

I can't add any insight, you are way ahead of me already. I'll also be interested in Dr. Olnes take.

Blasts not worth mentioning, wow!

And crowd sourcing? Did you invent that??

Hey Catherine!

I cannot take credit for crowd sourcing; I'm not sure who came up with that one.

Dr. Olnes opined that my disappearing Trisomy 8 could be the result of the Campath, but, given my increased need for RBC transfusions, he doesn't expect further response. His first line recommendation is Revlimid, though I've asked him about ezatiostat, as well.

So I'm in the hunt from promising new therapies for low-risk folks.

Have a great Sunday!

Greg

Hi Greg,

I have a question for you...How long after Campath is your CD4/CD8 ratio expected to be reversed? Could it be reversed because you still have some kind of auto immune attack going on in your system?

Hi Hopeful!

Dr.Olnes tells me that the Campath-induced CD4/CD8 inversion lasts about two years. I gather that Campath knocks down lots of different T-cells and B-cells, but maybe knocks down the CD4s even more than the rest.

Near as I can tell, it's an expected effect of the drug.

Take care!

Greg