Clinical Trial Fibrogen 2216
 

Last summer I participated in a clinical trial at UMass on Fibrogens 2216 for 5 weeks. I did not experience a positive response with this drug but looking back maybe I should have stayed on it longer. Anyone participate in a clinical trial with this drug or any others for treatment of MDS? What were the results.
Warren Rich
RAEB dx Feb. 2006

Fibrogen trial
 

My husband, David is currently on such a trial with Dr. Raza at UMASS. He's on day 87 of a 113 day trial. He's at the maximum dose (2500 mg), feels awful, nausea, loss of appetite, sharp stomach cramps, and even greater fatigue than he normally has--but he's sticking it out, because whatever results there have been seem to come after the trial is over. He is tansfusion-dependent, every 2 weeks, that hasn't changed--yet.
Judy

Fg2216
 

Your Dad's respnse sounds like mine. When I went to the higher does with Dr Raza I felt terrible so I opted out but my trans fusion frequency never got a whole lot better. I was 4-5 weeks then all of a sudden I went to two weeks. So I went to a Dr Voorhees at UNC Chapel Hill, NC and he did a bone biopsy and then put me on Dacogen. My results to date on Dacogen have been fantastic. If you want call me at 910-791-6745 and I will fill you in on the details.
Warren Rich
Wilmington, NC