ASH 2010 Highly Transfused MDS Patients Often Have Cardiac Iron Overload
 

2906 Highly Transfused MDS Patients Often Have Cardiac Iron Overload, as Shown by MRI Assessment

http://ash.confex.com/ash/2010/webpr...aper27429.html

Conclusions: Moderate and severe post transfusional cardiac iron overload was seen in 19% and 4% of regularly transfused MDS, respectively. The level of cardiac iron overload was well correlated to the number of RBC transfused. The impact of cardiac overload on LVEF was unclear except in pts with severe cardiac impairment (LVEF <35%) , possibly suggesting that iron overload is only one of the factors responsible for cardiac disease in many of those elderly patients.