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-   -   Long-term eltrombopag for bone marrow failure depletes iron (article) (http://forums.marrowforums.org/showthread.php?t=6702)

mola-tecta Tue May 17, 2022 02:46 PM

Long-term eltrombopag for bone marrow failure depletes iron (article)
 
https://pubmed.ncbi.nlm.nih.gov/35312200/

https://onlinelibrary.wiley.com/doi/...1002/ajh.26543

A very interesting and useful article about the iron chelation effect of Promacta/eltrombopag. Particularly interested in this due to my mother having serious trouble tolerating Exjade but has maintained on Promacta, and has seen her ferritin levels drop.

Matthew42 Tue May 17, 2022 03:54 PM

Quote:

Originally Posted by mola-tecta (Post 54811)
https://pubmed.ncbi.nlm.nih.gov/35312200/

https://onlinelibrary.wiley.com/doi/...1002/ajh.26543

A very interesting and useful article about the iron chelation effect of Promacta/eltrombopag. Particularly interested in this due to my mother having serious trouble tolerating Exjade but has maintained on Promacta, and has seen her ferritin levels drop.


So happy to hear this! :)

If I am not mistaken, it's just not the ferritin levels in the blood, but how much your cells absorb the iron? Promacta stops cells from absorbing iron.

I deeply appreciate your posting this.

Please take care.


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