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-   -   St Jude's BMT survival rate (http://forums.marrowforums.org/showthread.php?t=2265)

Marlene Fri Jul 15, 2011 07:51 AM

St Jude's BMT survival rate
 
St. Jude's improvement of survival rate for high risk leukemia patients.

http://www.sciencedaily.com/releases...0714120846.htm

JodyW Fri Jul 15, 2011 09:33 AM

St Jude's BMT rates
 
Marlene,
Thanks for the article. I notice all the articles talk about improved BMT for leukemia but would it also apply to BMT for AA. Is there a difference in success for different types of disease?

Thanks

Marlene Fri Jul 15, 2011 10:16 AM

Hi Jody,

I don't really know the answer to that but it would make sense that it would work just as well in AA where ATG has failed and there is no matching donor for child.

I think that's why it is so important to find out what you can from the different BMT centers on what protocols they use so you can make informed choice on where to go. You really want the least toxic, most effect protocol with good outcomes. Especially with GVHD. It saddens me to read about those who have successful BMTs but end up major GVHD.

Greg H Fri Jul 15, 2011 01:57 PM

Hi All!

Even though I'm and MDSer, I watched this AAMDS presentation (from March) on SCT for AA the other day and was very interested to learn about the differences in transplant for the two diseases.

The presenter, Dr. Noel, said one key difference is that, in MDS, you typically want a little GVHD, to help kill off the cancerous stem cells in the marrow. In AA, you don't have those bad stem cells to worry about, so the aim is to, if possible, completely eliminate GVHD. So there's a bit more of a balancing act in the MDS cases.

The whole lecture was really very fine; I recommend it.

Take Care!

Greg

Marlene Fri Jul 15, 2011 02:37 PM

Yeah, that makes sense. Same would hold true with AML/ALL.


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