[JEZ]

After successful treatment for AA with horse serum and Csa for two years, I developed kidney toxicity. I came off of CsA and am now taking generic Imuran, 150 mg per day. My platelets on CsA reached a high of 168,00. Since coming off of the CsA my kidney function thankfully recovered BUT my platelets have trended down: (May) 148K, (June) 133K, (July 16th) 88K, (July 23rd) 80K, (August) 80K, (October) 71K.....My doctor says if I go down to <60K she will put me on another drug (sp) tachrilamus but says it can also be toxic to the kidneys. I wonder if anyone know of alternative drugs to Csa??? If I completely relapse I am concerned that the rabbit ATG seems so ineffective (from reading posts on the forums) and I am 59 1/2 years old and not a great candidate for BMT... By the way, my RBC and Hg as well as WBC seem to be doing fine. When first dx's my Hg etc was awful.