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MDS + immunosuppressant therapy
Hello Jill,
From what I have read, a small percentage of patients with MDS may respond to immunosuppressant therapy with ATG and cyclosporine. Apparently you have more of a chance of responding to this therapy if you are young, (less than 60y.o.), have a hypocellular marrow, normal cytogenetics, low risk disease, evidence of a PNH clone and HLA-DR15 histocompatibility type. Do you know if you are positive for HLA-DR15? Certainly something to consider before transplant. Good luck. tytd
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possible low to int-1 MDS with predominant thrombocytopenia, mild anemia, dx 7/08, in watch and wait mode
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