Hi CMM,
Nobody knows the best doses for Dacogen (decitabine) or Vidaza. Since we are different we will have different results even when we get the same dose.
There are many trials with different doses of Dacogen like this one:
http://clinicaltrials.gov/ct2/show/N...ine+mds&rank=6
The study is done at MD Anderson - I think it is the best cancer clinic in the world. As you can see they test 10 mg Dacogen during 10 days and compare that dose to many other doses. One member of this forum got a lower dose of Vidaza in a 10 days cycle and did very well during one year.
Be careful when your WBCs are so low - avoid infections and go to the hospital if you get fever. Avoid everything that can decrease your platelets especially pain drugs.
Hope your counts will increase with Dacogen
!
Kind regards
Birgitta-A
71 yo, dx MDS Interm-1 May 2006, transfusion dependent, Desferal and Exjade for iron overload, Neupogen for low WBCs, Thalidomide and Prednosone for bone marrow fibrosis (platelets have increased from 22 to 66)