Hi Lindy,
This study -
http://ash.confex.com/ash/2010/webpr...aper34476.html | Author
2943 Platelet-Associated IgG May Be Associated with Thrombocytopenia In Patients with Myelodysplastic Syndromes
- found out that MPV was significantly higher in patients with platelet count < 100 x109/L( median, min-max: 9.38, 6.9-23.1 vs *8.46, 4.88-12.83 ; p<0.001, Wilcoxon rank sum test).
Your doctor can relatively easily find out if you belong to the group of MDS-patients where immune destruction of platelets could be an additional factor in the genesis of thrombocytopenia.
"Thus, we propose that a combination of a simple index as MPV and a highly sensitive and easy to perform screening test for PAIgG as PIFT could be applied to select a subset of MDS patients in which we would be able to prevent the overuse of unnecessary platelet transfusions and who could be candidates for an immunosuppressive therapeutic approach. "
ITP could be an approach helping you to get medicaments like NPlate, but the actual studies seem not promising the optimum of safety for MDS-patients.
Hope i could help.
Regards,
Margarete