His dosage keeps getting changed. 2 weeks ago (I think. Maybe it was last week? It's becoming a blur) he was on 225 2x a day, his trough was 133.
It was last week, I got my 3 ring binder out with all the lab results. His kidneys seem to have some trouble with the higher dosage, but the doc wants his level to be closer to 200. His Urea Nitrogen at the current dosage is 28 (range is 6-23).
Thanks for the help.
Quote:
Originally Posted by Hopeful
Hi edithr,
145 lbs = 65 mg
If he is take 475 mg/day than he is taking slightly more than 7 mg/kg/day which does not seem crazy-high. However, it is believed by some doctors that dosages above 5 mg/kg/day (or 325 mg/day for your son) only give toxicity without added benefit. Keep an eye on his trough. It could start increasing rapidly, at which time you could discuss with the doctor lowering his dosage. A lot of doctors like to try the maximum tolerable dosage right after ATG for the biggest "shock-and-awe" effect on the rogue cells.
Cyclosporine peaks about 2 hours after taking. It would be great if just changing the timing of his showers made them more tolerable. I can't remember if there was a correlation for me. I just remember it was misery until I lowered my cyclosporine dosage!
|
__________________
Edith, mom to Eric, dx 2/11 at age 15 with SAA, began ATG/CsA 3/11, switched to Tacrolimis 8/11, off all meds 9/11 and is now considered to have bone marrow failure not otherwise specified.
|