Hi,
The Mayo Clinic in New York recommended an IV Copper dose of between 2 to 4 mgs/day for 3 weeks. When I was in hospital for a week I had 4mgs/day but the other doctors in the practice my doctor belongs to weren't in favour of giving me any copper at all, so as a compromise, my doctor reduced the dose to 2 mgs/day as an outpatient. This dose hasn't been effective so I'm having a further week of IV Copper (week No 4) with an increased dose of 4mgs/day. Ongoing treatment will depend on my response to this increased dose. The response is measured by the Copper and Ceruloplasmin levels rather than CBC results because the CBC fairly much normalises with Copper levels of less than half normal parameters.
My doctor feels that for neurological stasis/improvement, it's important to have sustained Copper levels well within the normal limits.
There has been some good news with Tina. She has started walking a few steps by using both her hind legs together, kind of like a bunny hop. She's not in pain and she's still happy so I'll keep on hoping for progress. I started giving my dogs glucosamine last year but my other dog, Gidget, developed a GI bleed and ended up in hospital for a week. There was no connection established between the glucosamine and the bleeding but I stopped giving it anyway. Now I give them Sharks Cartilage but I will definitely get some Green Lipped Mussel. Thanks for the tip.
Regards
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Copper deficiency bone marrow failure (MDS RAEB 1), neuromyelopathy.
FISH reported normal cytogenetics but gene testing showed
Xq 8.21 mutation
Xq19.36 mutation
Xq21.40. mutation
1p36. Mutation
15q11.2 deletion
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