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Hi Irum!
Sorry to hear about your Dad. I also have lower-risk MDS.
Synthetic EPO doesn't work for everyone -- only for a subset of patients who aren't producing enough natural EPO. Normally, if the patient's natural EPO level is 500 or higher, there is a very small chance of response.
In the US, the next drug to try might be Revlimid (lenalidomide), Vidaza (5-azacitadine), or Dacogen (decitabine).
Did the bone marrow biopsy reveal that your father had any irregularities in his chromosomes? That information can sometimes provide a clue about what drug would be best.
Take care!
Greg
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Greg, 59, dx MDS RCMD Int-1 03/10, 8+ & Dup1(q21q31). NIH Campath 11/2010. Non-responder. Tiny telomeres. TERT mutation. Danazol at NIH 12/11. TX independent 7/12. Pancreatitis 4/15. 15% blasts 4/16. DX RAEB-2. Beginning Vidaza to prep for MUD STC. Check out my blog at www.greghankins.com
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