Quote:
Originally Posted by celebrations
I was informed, that there would be three cases which would alter my situation immediately and would lead to a SCT-decision.
- a steady decline of white counts and platelets ( I am between 3,0-4,0 wbc and 250 000 plts)
- an increase of blasts over 5% (I don't have any yet)
- an additional chromosomical aberration (I have my trisomy 8, between 50 and 60 % also for six yrs now)
Each of these changes would mean a severe progression of the disease.
And then SCT will be my last option.
Never before.
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Hi Bergit!
I, too, am sorry to hear about your friend. But it's great to hear that you have such a neat support group.
Your list of reasons for transplant hews very close to the rationale outlined by Dr. Matt Kalaycio of the Cleveland Clinic in the
presentation that Lisa V and I have recommended.
He says the Cleveland Clinic never transplants low-risk MDS patients, because, even though the success rate is highest with that group, that group has other options.
Reasons they proceed to transplant:
High IPSS Score
High Probability of conversion to AML
Intolerable transfusion requirement
Severe Neutropenia.
That's pretty similar to the criteria your doctors use.
Take care!
Greg
__________________
Greg, 59, dx MDS RCMD Int-1 03/10, 8+ & Dup1(q21q31). NIH Campath 11/2010. Non-responder. Tiny telomeres. TERT mutation. Danazol at NIH 12/11. TX independent 7/12. Pancreatitis 4/15. 15% blasts 4/16. DX RAEB-2. Beginning Vidaza to prep for MUD STC. Check out my blog at
www.greghankins.com