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MDS, angiodysplasia and thalidomide
Hello,
my mother (71yrs) was diagnosed with MDS (AREB2, 12% blasts) in April 2010, and went trough 8 cycles of Vidaza until December 2010 with little improvement (10% blasts). Since then, she has been receiving only supporting care, with 1 transfusion every 10-14 days (HgB from 7 to 9.5). Recently her HgB dropped to 6, because of probable angiodysplasia in the intestine causing blood emorragy (dark blood in feces).
On the one side, gastroenterologist says this is not linked to MDS, and suggest treatment with thalidomide or octreotide (somatotatin).
On the other side, emathologists say this is likely linked with MDS, and are skeptical about the use of thalidomide.
Has someone had similar experiences, with angiodysplasia, MDS and maybe thalidomide? What are thalidomide side effects?
Many thanks for any answer or suggestion,
Paolo
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Paolo, my mother aged 70 diagnosed AREB-2 in March 2010, currently (Dec 2010) on Vidaza
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