Hi Paolo,
You don't write anything about your mother's platelets and WBCs - when the platelets are low we can get bleedings often from the intestines.
Thalidomide has many adverse effects - neuropathy (the nerves to the feet don't function properly) and constirpation are common
http://www.medicines.org.uk/emc/medi...IRABLE_EFFECTS
I have been taking Thalidomide - a very low dose - since June 2010 with very good results. I got low white blood cells when I took Thalidomide 50 mg/day and I only tolerate 4 caps/week. Then Thalidomide should be combined with Prednisone or a similar drug for best results. I still take Prednisone 5mg/day. I have no adverse effects except the low white blood cells initially.
Kind regards
Birgitta-A
72 yo, dx MDS Interm-1 2006. transfusion dependent from dx until Sept 2010 after 3 months with Thalidomide. HGB now 134.