Quote:
Originally Posted by Greg H
Hi amkjud!
On to the diagnosis . . .
All these "dys" things are cells that should be evolving into normal blood cells, but instead are broken in one way or another. That brokenness -- not the chromosomal abnormality -- is the hallmark of MDS. Lots of MDS people have normal chromosomes, but broken blood factories.
I hope that helps. It's all pretty confusing. If you son doesn't have any of these broken blood cell precursors in his BMB, then I think it would be odd that he's been diagnosed with MDS.
Take care!
Greg
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diagnosis is not certain but that's the direction they're going in.
one bmb showed some megakaryocytosis with micromegakaryocytes. also high hemoglobin in circulating blood (which was the original indication for bmb after all other workup negative).
chromosome abnormility is 7q- (7q abnormalities common in MDS and linked to poor prognosis in AML). doctors seem most concerned about this.