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MrHandy2013,
I applaud your determination to keep fighting back, and I understand your decision to go ahead with a transplant. It's clear that these diseases aren't going to disappear on their own and it's fortunate that you're transplant eligible and otherwise healthy.
A sibling match is clearly a plus. I assume that you are in your 50s or early 60s so waiting years more could make a transplant less of a possibility (even if your brother stays healthy enough). If you're going to have a transplant, the sooner the better.
If you could coast through the coming years with only transfusions then that would be another choice, but needing transfusions so frequently isn't a very sustainable way of living. You'd be tied to the hospital and your constant need to check blood counts.
None of your choices is risk-free, but that's the nature of MDS. I wish you the best of luck and hope you'll keep us up to date.
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