Quote:
Originally Posted by Greg H
Hey Ann!
As I understand it, Vidaza and Dacogen both work in pretty much the same way. They are both "hypomethylating agents," which means they affect important processes at the level of DNA.
Greg
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They are demethylators/hypomethylators. The idea being that hypermethylation(too many methyl chains) inhibits gene expression and by releasing the methyl chains the genes are able to express themselves.
I've had 4 rounds of Vidaza so far with great results, and no side effects luckily. My understanding is it depends on the docs you use and the experience they have with it For example if your treated at Cornell-weill they'll go with vidaza, over at mt Sinai they go with Dacogen. Hope that helps.