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My husband had 6 rounds of Vidaza before going to transplant.
When he had them via IV, they took longer but I thought that he did better. He did not have nausea and discontinued the meds they gave him before treatment as they made him severely constipated.
He later opted to have the shots in the stomach. Those left him with horrible red splotches and sore spots at times. However, he preferred these due to the time factor. IV took over an hour--shots took about 15 min.
I think it is a very personal choice. If it were me, I would have preferred the IV. The drawback there is that you have to keep the line (if they leave it in) dry. After several treatments, it can be difficult to find a viable vein.
Probably the best compromise, if your doctor goes along with it, is to do IVs part of the time, then injections in the stomach to give veins a rest.
What ever the side effects, nausea, constipation or headaches, there should be some medicine available to help with these.
Best of luck to you.
Deb
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