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thanks for responding. although it says "normocellular" his number is 35% (which seems low to me, as he's 51 years old). Yes, we did see Dr. Paqette last Friday who is saying he's not sure it's MDS and that the biopsy needs to be redone. His only counts that are real low are his platlets. His hemo is 12 and his whites are 4. his mcv's are high though.
FINAL INTEGRATED DIAGNOSIS WITH CYTOGENETIC STUDIES:
BONE MARROW, RIGHT ILIAC CREST (ASPIRATE SMEAR, TOUCH PREP,
CORE BIOPSY SECTION, CLOT SECTION):
- Chromosome analysis (case Z14-12857) reveals trisomy 8 in
16/20 cells analyzed, consistent with myelodysplastic
syndrome (MDS)
- Normocellular marrow core biopsy with multilineage
hematopoiesis
- No excess blasts, no significant dysplasia, and negative
for lymphomatous involvement (See comment)
- Aspirate smears contain no marrow spicules
- Flow cytometric studies detect no monotypic B-cells
- Small non-paratrabecular lymphoid aggregates,
non-diagnostic
- Trace iron stores present on decalcified bone marrow
biopsy sections
INTEGRATED COMMENT:
Morphologic evaluation is limited due to absent marrow
spicules on the aspirate smears. Dr. Pinter-Brown is
notified of the cytogenetics results and final integrated
diagnosis on 7/08/14.
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