Joe,
(a) yes it is common for PLT's to drop, and depending on the individual, it depends on how long it will take to recover. Your Mom's PLT's were already pretty low...
as for (b), (c), and (d) again it's different for everyone, age and overall response are big factors...
I did Dacogen, which is extremely similar to Vidaza last year, and here are my numbers by date:
Code:
Component Standard Range 7/18 7/30# 8/15 8/22 8/29 9/09# 9/16 9/20 10/7
RDW-CV 11.6-14.4 % 16.1 15.1 13.8 18.5 17.0 14.3
RDW-SD 35.1-43.9 fl 51.5 48.1 40.9 55.9 53.5 45.0
HGB 13.7-17.5 g/dl 11.0 11.0 9.9 10.6 11.9 13.9 14.4 13.9 15.4
HCT 40-51 % 31.7 32.4 27.8 30.3 35.4 41.1 43.5 40.6 45.7
PLT 150-400 K/ul 95 91 51 60 209 333 249 176 209
RBC 4.63-6.08 M/uL 3.56 3.64 3.29 3.45 4.07 4.76 5.01 4.74 5.43
WBC 4.2-9.1 k/ul 3.2 3.5 2.6 1.7 1.8 2.2 4.0 4.1 3.5
NEUT% 34-68 % 53 62 52 31 32 46
NEUT 1.8-9.0 K/uL 1.7 2.2 1.4 0.5 0.6 1.0 2.7 3.0 2.1
LACT-DEH 313-618 U/L 670 598 --- 688 --- 517 --- --- 557*
BILIRUBIN 0.2-1.3 mg/dL 1.5 1.1 --- 1.8 --- 1.0 --- 1.0 ---
# started Dacogen chemo
*estimate based on different testing ranges
__________________
Married, father of three daughters; now 46; diagnosed w/ Major form MDS 6/18/2013; had low counts across the board; Multiple chromosome abnormalities; Finished 2nd round Dacogen 9/13; SCT - Oct. 31, 2013; Sibling match 10/10
; 5.5% blasts down to 3%, now 1% (post BMT)