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The most important factor to consider is where your father will get the best care. That requires expertise with MDS, which not all physicians, physician groups, or hospitals have. If you need help identifying the MDS experts in your area, the AA&MDSIF, The MDS Foundation, and other users of these forums can probably help, and doctors you know may be able to provide recommendations as well.
The next factor is how well you can work with a new oncologist, which you won't know until you've had at least one appointment with them. A good doctor will be wiling to listen to you, explain things, and let everyone be part of the team.
Any doctor will be unavailable to you at times. It's not just about vacations. The best oncologists I know keep up with their profession by attending medical meetings and conferences, and the very best of them are the doctors speaking at those conferences. Having a medical team that lets one doctor take over temporarily for another can make up for that.
Other factors to consider when switching doctors are the location (how far you have to travel and how easy or hard that will be for your family) and which doctors your insurance covers.
Logistically it's easy to change doctors. Contact the new doctor, make sure they will accept you as a patient, make an initial appointment, and ask them how best to transfer your medical records for them. Although you can go to the old doctor's office and use your right to see (and photocopy) your medical records, in these days of electronic records there's probably an easier way that your records can be transferred between the doctors.
If the old doctor is receptive to feedback it's OK to explain that you are switching to a group practice where there will alway be experts on call. Doctors, like any other businesspeople, would like to know why they are losing or gaining customers, and they know that you need to do what's best for your family.
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