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@bailie,
The primary indicator of relapse was the result of my bone marrow biopsy in August which showed multiple trisomies in 1 of the 21 cells reviewed by the pathologist. My cells still looked normal and there weren't any increases in blast cells. The evidence of dysplasia was not present, but the cytogenetics said otherwise. I had the trisomy 8 that was a part of my original diagnosis plus 3 other trisomies in that cell. The other giveaway was that my blood counts were dropping, in particular the platelets. This was all of course complicated a little by a drug interaction that I had that caused some HUS/TTP. Stopping sirolimus helped, but a full blood count recovery did not accompany the withdrawal which is why we did the biopsy.
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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