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Old Sat Feb 21, 2015, 12:26 AM
Hopeful Hopeful is offline
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Join Date: Jan 2009
Location: California, USA
Posts: 769
Hi rukalukavina,

Your comments made me remember that I did feel this incredible fatigue in the afternoons after intense exercise when I was about 3-4 years out from ATG and also was tapering my cyclosporine dosage.

I did have a period of 9 months or so when I was completely off of cyclosporine, and I remember feeling like I new person, even though I didn't really think that I felt bad before. Maybe my body adjusted to the new normal??

I am back on a low dose of cyclosporine and don't notice the fatigue in the afternoons anymore.

A possible theory for your fatigue is that although your counts may be normal, your marrow may still not be of normal cellularity. So, your blood pregenitors may be working extra hard to pump out the blood cells???

In any case, listen to your body, don't give up, and know that it gets easier

P.S. If you are female, also get your iron checked.
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58 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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