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Avoiding PRBC transfusion reactions...
These can vary from person to person. I had some mild to severe reactions when starting on this road in 2008. All such problems were ended by having a set of premeds BEFORE a PRBC transfusion. Also it's necessary for me to have CBC draws two days before transfusions so that a proper cross and type by the blood bank can find compatible donations.
Something to consider before giving up. Good Luck! 
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Ric: Low-risk MDS (blasts <4%); 4 cycles Revlimid no positive response; PRBC transfusion dependent; so far, 392'units' over 8 3/4 years; BMB #4 (15/04/01) shows evolution to AML (blasts 20-30%  ) 47,XY,del(5) (q22q35),+21[24][cp24]/46,XY(1).
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