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Old Wed Jan 4, 2017, 03:32 PM
Fordad Fordad is offline
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Join Date: Jan 2017
Location: Arkansas
Posts: 8
Question Questions about agent use and length

Good Afternoon everyone. I have been doing a lot of research, as I know you all have as well, but I am left with questions that maybe don't have definitive answers.
My father was diagnosed with MDS RAEB II in April of 2016. He has some other co-morbid conditions but for the most part was "healthy". Initially he was started on Vidaza and after 4 rounds and a BMB his oncologist concluded that there had been no improvement. He was then started on Decogen and has completed 4 rounds on it as well. He just completed another BMB but the doctor has little hope of any improvement. My father is 76 years old and has been told that stem cell transplantation is not an option for him so his only other choice would be intense chemo but, due to his age and other conditions, it is not recommended.
I feel that the Vidaza was stopped prematurely, from what I understand from the research, 4 cycles is when it begins to start working. He has been getting blood and platlet transfusions at about 7 to 10 day intervals for several months now and of course now I worry about iron overload. I feel like they are giving up too quickly. The last CBC auto diff he had showed the following values: WBC 3.6, Neutro 14.9%, Lymph 76.1%, RBC 2.54, Hgb 7.1gm/dL, HCT 22%, MCV 86.5, Plt 17, MPV 6.7.
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