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Old Tue Jul 8, 2008, 03:48 PM
Birgitta-A Birgitta-A is offline
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Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
For Suzanne Vidaza

Hi Suzanne,
When I look at the link to clinical trials
http://clinicaltrials.gov/ct2/results?term=mds+vidaza
I canĀ“t find any trial where they give Vidaza 10 days. There is one trial where the give the drug during two weeks but as far as I understand the trials where they give Vidaza 5 days and then wait 23 days before they start again with Vidaza have the best results.

The MDS patients often have a vulnerable bone marrow and the healthy stem cells need time to recover between the Vidaza treatments.

If your mother is offered a trial with Vidaza and/or MGCD0103 it could be good for her to be in a trial because both drugs are effective (but as other members write there is no cure except stem cell transplantation.

If she only is offered to participate in a trial with Vidaza it is perhaps better to let her doctor prescribe Vidaza individually - then he/she can decrease the dose if it is too high for your mothers bone marrow and then she can get it iv (in the Vidaza/MGCD0103 trial Vidaza was given sc).
Kind regards
Birgitta-A
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