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Old Sat Jan 3, 2009, 03:19 PM
Birgitta-A Birgitta-A is offline
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Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Father with MDS

Hi run4peach1,
Good that your fathers bone marrow seems to recover when it is left alone for some days !

They could have tried Aranesp before Vidaza and Dacogen - Aranesp is a very common supportive therapy and doesn´t have any adverse effects on the bone marrow.

Aranesp and the other EPO-drugs don´t work so good if the patients own kidneys make much serumEPO and try to stimulate the bone marrow. If the patients serumEPO is more than 500 Aranesp often doesn´t have any effect (my serumEPO was more than 800 and I never tried Aranesp).

Ask how much your fathes serumEPO was before the first transfusion?

Here is an abstract about an EPO-drug:
http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

As you can read 67 % of the patients responded and more patients responded with a combination of EPO-drug and a drug like Neupogen for white blood cells.
Kind regards
Birgitta-A
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