Hi Helen,
Sorry I didn’t see your questions though I read Marrowforums every day – they disappeared behind some other post
.
Interleukin-1 (Il-1) fights infection by (1) making it more easy for white blood cells reach infections and (2) having an impact on a part of the brain called hypothalamus thermoregulatory center, leading to an increased body temperature which expresses itself as fever. The increased body temperature helps the body's immune system to fight infection.
Interleukin-6 (Il-6) IL-6 mediates fever. In the muscle and fatty tissue IL-6 stimulates energy mobilization which leads to increased body temperature.
Both are attacking inflammation – fever is one of our weapons when we fight infections.
Both are made by white blood cells and always found in the blood.
Neupogen is a growth factor for white blood cells. It stimulates the type of white blood cells called granulocytes (among them neutrophils) and is produced by bacteria into which has been inserted the human granulocyte colony-stimulating factor gene.
Neupogen is only used when the white blood cells are critically low. The important white blood cells called neutrophils are about 50 % of the white blood cells so when your white blood cells are 2.8 your neutrophils are about 1.4. Less than 1.5 neutrophils is called mild neutopenia – you should be very careful and try to avoid all kinds of infections because your bone marrow has problems to make neutrophils that can fight infections.
http://www.neutropenia.ca/about/index.html
It is very difficult to know why you have fever
. In any case you should control it - as you probably already do - morning and evening and seek help if it is going up.
Kind regards
Birgitta-A