I agree that the iron is quite high just after 18 transfusions. You may want to check to see if she has hemochromatosis (hereditary iron overload type). They can test for this. Do you know if she had her iron checked before she started transfusions? That would be good to know. High iron can impact the bone marrow. A FE of 1500 in anyone needs to be explored so I'm not sure what your doctor meant by his statement. FE readings can and do bounce around especially if there's any inflammation or infections. So it's good to have it tested a few times to see what the trend is over time.
Typically, they check iron levels, B12, folate, copper, zinc and vitamin D levels. See if you find out that information.
Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of January 2017, FE is 233, HGB 11.7, WBC 5.1/ANC 4.0, Plts 146K.