You first need to rule out B12 and Folate deficiencies, as these can negatively impact blood cell production and mimic other diseases. Aplastic Anemia is a possibility, but this diagnosis is usually made when all others fail. Copper and arsenic are other tests that are typically checked while looking for a diagnosis.
If everything else comes back normal, and her diagnosis is aplastic anemia or hypocellular MDS, then I would discuss with her doctor trying cyclosporine again at the proper dosage. Make sure the doctor is closely monitoring her kidney and liver function while she is taking it.
Your mom is lucky to have you supporting her through this!
52 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. Tried slow cyclosporine taper over 4+ years. Platelets fell, so back on cyclosporine. Trisomy 6 clone in 5% of cells.