Hi Bob,
My doctor who is a specialist in Vidaza treatment for MDS says that nobody knows the best dose of Vidaza. One member of this forum is getting a low dose during 10 days with very good result.
Here is a link to results from a trial with 3 different doses. Group B corresponds to your mother’s dose an has a 65% response rate:
http://ash.confex.com/ash/2009/webpr...aper21649.html
You are right about her low platelets. About 65% of the patients get thrombocytopenia during Vidaza treatment. One member of this forum (Kirby) is getting Promacta for his low platelets with good result as you can read in posts from him.
Your mother's other results (blasts, karyotype, WBCs and Hgb) are very good
and perhaps it is more important to treat the low platelets than her bone marrow.
Kind regards
Birgitta-A
70 yo, dx MDS Interm-1 May 2006, transfusion dependent from dx, Desferal and Exjade for iron overload, Neupogen 2 injections/week for low WBCs