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Old Sun Jun 12, 2011, 01:17 PM
Birgitta-A Birgitta-A is offline
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Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Iron overload

Hi Bergit,
You probably already know than iron overload can damage the liver and this can be followed by controlling the liver tests - ASAT and ALAT (I don't know what these tests are called in the US). In fact increased liver tests is one reason to start iron chelating in many countries. You know we manage well with one third of the liver, so it is OK if the tests are elevated during some months.

Iron overload can damage the pancreas too so we get less insulin and increased blood suger.

Remember that it takes years for serious symptoms to develope.

"In the liver, which is the main repository of iron in patients with transfusional iron overload, serious clinical consequences can arise, such as increased liver tests... Iron overload also can cause progressive dysfunction of the endocrine glands, leading to diabetes..."

http://onlinelibrary.wiley.com/doi/1...ncr.23280/full
Kind regards
Birgitta-A
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