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Old Sat Aug 9, 2014, 04:25 PM
sbk007 sbk007 is offline
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Join Date: Apr 2013
Location: NY
Posts: 322
Great news Arnav is doing well and feeling good. Happy to hear that.
The way I understand it is chimerism refers to the ratio of donor cells to recipient cells. From what I've observed on this board is that its not uncommon to have a mix after 30 days. In any case as you know cyclosporine suppresses the immune system in the hopes to prevent the immune system from attacking the donor cells(GVHD). However, by suppressing the immune system you might be preventing the immune system from attacking the "Bad cells". When they cut the dose of cyclosporine, the immune system can now eat the remaining "bad cells" so that you become 100% donor. There was one member on here that stopped taking a drug called prograf to reduce chimerism. Some doctors insist that a little GVHD is good for that reason. I hope that helps and continued success to Arnav and you as he recovers. Sounds like he is doing GREAT!! and will be in the clear soon.
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