[Jordan]

With TLK199, I take 5,000 mg each day for 7 days and then am off for 2 weeks. At Moffitt Cancer Center, I am the only one of 14 who started the trial still on it. Side effects are body smell like a machine shop, some nausea, and one or two times pills get stuck in the throat. I finished my 6th cycle and the reason that I am still on it could be due to my body mass as I am 210 lbs and 5'10" while the others in the test were smaller in size along with other health issues.

Just got results of my third biopsy of 2007, blasts declined from 9% to 6%, WBC 7.7, Hem 12.0 & Platlets 20. Therefore I am continuing with TLK199 treatment as it held WBC in normal range, improved Hem from 9.7 to 12, but has not helped Platelets. I saw this week for the first time Dr. Alan List at Moffitt and we decided to go off the trial as it was not helping my platelets. I will be off everything for 2 monthsand then a BM biopsey again.