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Old Thu Nov 7, 2013, 11:33 AM
curlygirl curlygirl is offline
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Join Date: Jun 2013
Posts: 151
PNH in white vs. red blood cells

Hello! My son's PNH is secondary (probably) to his Aplastic Anemia. Back in June prior to his ATG he was tested for PNH and had a 19% clone, but the page I had didn't distinguish amongst the type of cells. He had a follow-up test two weeks ago that actually broke the clones out. The totals were: 2% red blood cells (RBC), 5% granulocytes, and 12% monocytes. It also said that the RBC clone had increased since June, but the white blood cell (WBC) clones had decreased. For some reason I thought that PNH only affected the RBCs, maybe because it often caused hemolysis. My son did have hemolysis a lot prior to his ATG treatment, but now I'm surprised to see that his RBC clone would have been lower than 2% to cause that level of hemolysis. Can the WBC clones also be the cause of hemolysis? I guess I'm curious about what happens when white blood cells have PNH clones. My son always does have high monocytes. They were 13% prior to his ATG in June, and were 9% at his last visit this week.
Thanks!
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