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It would help to know what your other options are, Susan. If you don't have a BMT match or are past the recommended age, I would definitely try a second ATG.
It sounds as if you have had some degree of response to the first round, so that is reason to be a bit more optimistic about the second. Your Plts are about where Ken's were following his first ATG. He did become RBC tx-ind too, but never attained the levels he has reached since getting the second round (procrit helped too). I'd talk to your doctor about the possibility of increasing the duration/dose the second time, as we did. Unless you had a problem with the horse, I'm not seeing a reason to switch, particularly now that studies have found it to be more effective than rabbit.
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-Lisa, husband Ken age 60 dx SAA 7/04, dx hypo MDS 1/06 w/finding of trisomy 8; 2 ATGs, partial remission, still using cyclosporine
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