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Old Wed Aug 28, 2013, 03:11 PM
Hopeful Hopeful is offline
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Join Date: Jan 2009
Location: California, USA
Posts: 766
It is possible that your son has an early form of AA or hypocellular MDS or something else. As you said, hypocellular bone marrow is atypical for ITP.

Here is a good article that discusses, among other things, checking for elevated EPO and MCV which may be indicative of evolving AA:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128894/

Having a normal FISH means that your son does not have any cytogenetic abnormalities, which is good. It doesn't rule out MDS though.

Hope they can figure this out quickly! Don't be afraid of getting a second opinion at another center specializing in bone marrow failure disorders. The more eyes looking at this, the better.
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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