Hi bandit224,
I agree with DanL, in my non-expert opinion, your BMB doesn't seem to indicate MDS. Although you have dysplasia in some of your cell lines, it is only mentioned as "minor, minimal, or mild". With MDS, the report would indicate
significant dysplasia involving over 10% of the cells.
Also, your MCV is normal. I think this number is usually elevated if your marrow is under stress.
Obviously, something else is going on given your worsening symptoms and low M:E ratio. Have you had any exposures to drugs or chemicals? Are you taking any supplements? Do you have bleeding or GI issues?
If you haven't already, check out this pernicious anemia forum for other possibilities as to why the shots aren't working.
https://healthunlocked.com/pasoc/posts
Good luck in your search!