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Refractory anemia with excess blasts-1 (RAEB-1)
One or more cell types are low in the blood and look abnormal in the bone marrow. The number of blasts in the bone marrow is increased; but is still less than 10%. The blasts do not contain Auer rods. Blasts may be present in the blood, but they make up less than 5% of the white blood cells.
The chance of RAEB-1 turning into acute myeloid leukemia is about 25%. This type of MDS has a poor outlook and most patients die within 2 years.
Refractory anemia with excess blasts-2 (RAEB-2)
This type of MDS is similar to RAEB-1 except the bone marrow contains more blasts – between 10% and 20% of the bone marrow cells are blasts. The blood also contains more blasts: between 5 and 19% of the white blood cells in the blood are blasts. The blasts may contain Auer rods. Any one (or more) of the cell types can be low in the blood and look abnormal in the bone marrow.
The chance of RAEB-2 turning into acute myeloid leukemia may be as high as 50%.
This is from the American Cancer Society
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age 70, dx RAEB-2 on 11-26-2013 w/11% blasts. 8 cycles Vidaza 3w/Revlimid. SCT 8/15/2014, relapsed@Day+210 (AML). Now(SCT-Day+1005). Prepping w/ 10 days Dacogen for DLI on 6/9/2017.
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