Hi Neel,
We still don't know which patients that will respond to decitabine, so nobody will know if your father belongs to the patients who will improve. In this study the overall improvement rate (OIR) was 23%.
https://ash.confex.com/ash/2011/webp...aper41286.html
The most frequent drug-related adverse effects were low neutrophils, anemia, low platelets, fatigue, and low WBCs.
The adverse effects will come after the first cycles and the response a little later. It is not possible to tell how many txs that will be needed.
We can only hope that your father will respond if you try this treatment.
Kind regards
Birgitta-A