Hi DianeD,
How terrible with transformation to AML in connection with Promacta treatment! Then we all know that Promacta probably is just as dangerous for us as the other platlet stimulating drug Nplate that caused increased blast cells in 8 of 44 MDS patients. In most patients the blast cells decreased when Nplate was stopped.
As far as I know only one other member, Kirby Stone, has received Promacta (since June 2009) and he has had good results.
There are 2 trials going on with Promacta (Eltrombopag) in MDS patients. At the ASCO Conference June 2010 they had an abstract about the preliminary result from the study with patients with advanced MDS - in fact they had AML because the blast cells in the bone marrow should be more than 20%.
The abstract did not tell us anything about the results because it was written many months before the conference. At the conference they showed an updated poster but that is not published anywhere so we have to wait until they publish the results somewhere else.
http://abstract.asco.org/AbstView_74_53792.html
Hopefully your WBCs will decrease when you don't receive Promacta!
Kind regards
Birgitta-A