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Promacta for platelets with MDS
Hi Diane and all,
I started Promacta 6/3/09 and have continued to use it at 75mg/day. I have MDS that transformed to leukemia, blasts 36% 10/2009. I'm on Thalidomide since 6/22/09, Dacogen low dose since 10/09. Blasts reduced to 14% on 2/10. I've continued on the 3 drug regimen and my counts are fairly stable.
The transformation to AML was probably due to the MDS, not the Promacta. I've continued on the 3 drug regimen and my counts are fairly stable. Promacta seemed to increase my platelets somewhat, not sure how much but prior to starting my platelets were as low as 9-12 and today they are in the 20-low 40's.
It is difficult to say what is really working in my case, I'm just glad something seems to be holding the counts. I'll have another BMB in July, hopefully the blasts are not higher.
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Kirby71, RAEB2 dx 2/04, Thalidomide 30 mo, Revlimid 18 mo, No resp Vidaza
6/09 2nd Thalid use, Promacta, Lowdose Dacogen added 10/09 at 40% blasts. 5/11 BMB-blasts 8%.
2/11 2nd Revl restart=good resp, Platelets drop 6/11, 3rd Thalid,+Nplate+Dacogen. 7/12 Cnts stable for 10 mo.
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