Hi cheri,
You know the International Working Group criteria for response in MDS are quite difficult to obtain – most patients are satisfied if they only get better without fulfilling the criteria.
Here are the criteria for
Hematologic Improvements
Red Blood Cells:
Major: Transfusion independence or >2 g/dL increase in hemoglobin
Minor: 50% decrease in transfusion requirements or 1–2 g/dL increase in hemoglobin
Platelets
Major: Platelet transfusion independence, or increase of 30,000/μL if less than 100,000/μL at baseline
Minor: 50% or more increase in platelet count (at least 10,000/μL) if less than 100,000/μL at baseline
Neutrophils
Major: If ANC <1,500/μL, increase of at least 100% or absolute increase of 500/μL, whichever is greater
Minor: If ANC <1,500/μL, increase of at least 100% but absolute increase of <500/μL
http://www.moffitt.org/ccjroot/v11s6/pdf/03.pdf
Kind regards
Birgitta-A